Scaffolds in Tissue Engineering

(Department)  Biomedical Engineering         (Division)     
 (Level and Major)           

Course Title              Scaffolds in Tissue Engineering                                     
Number of Credits       3             Prerequisite  

Course Description:
This course is an introduction to fabrication and characterization of tissue engineering scaffolds.
Course Topics:
  • Introduction to tissue engineering, applications and history
  • Definition of a suitable scaffold
  • Biocompatible biopolymers
  • Biocompatible synthetic polymers
  • Bioceramics
  • Scaffold fabrication techniques: Phase Separation, Emulsification/Freeze-drying, Solvent Casting & Particulate Leaching, Textile Technologies, Electrospinning
  • CAD/CAM Techniques for scaffold fabrication
  • Hydrogels and bioprinting
  • Scaffold surface modification
  • Scaffold biocompatibility evaluation
  • Scaffold design for a specific patient
  • Scaffold biodegradation mechanisms
  • Scaffold degradation tests
  • Effects of biodegradable implants on host tissue
Reading Resources:
  • Robert Lanza, Robert Langer, Joseph P. Vacanti, Principles of Tissue Engineering, Elsevier, 2014
  • Yoshito Ikada, Tissue engineering fundamentals and  applications, Elsevier, 2006
  • Peter X. Ma, Jennifer Elisseeff, Scaffolding In Tissue Engineering, CRC Press, 2006

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